Research Papers (RP)
http://ir-library.kabianga.ac.ke/handle/123456789/112
This collection contains publications done by University of Kabianga scholar2024-03-27T22:42:24ZOn Projection Properties of Monotone Integrable Functions
http://ir-library.kabianga.ac.ke/handle/123456789/793
On Projection Properties of Monotone Integrable Functions
Olwamba, Levi Otanga
This research formulates an (i − 1, i) - dimensional structure of µ
(i−1,i)
|f|p -vector measure integrable functions
for i = 1, 2, ...n. Fixed point projection properties of a vector measure are appplied to determine the
measurability of sets in the domain of integrable functions. Measurable sets of the form ΠiA
(i,i+1)
i−1
are
partitioned into disjoint sets ΠiA
i
i−1 of finite measure.The obtained results demonstrate utility of concepts
of vector measure duality, continuity from below of a measure and monotonicity of a vector measure in
integrating functions.
Research Article On Projection Properties of
Monotone Integrable Functions
2024-02-29T00:00:00ZUse of Fish Somatic Indices to Assess Pollutant Exposure and Effects: A Case of Two Urban Rivers and a Wastewater Sedimentation Pond in Lake Victoria Basin
http://ir-library.kabianga.ac.ke/handle/123456789/792
Use of Fish Somatic Indices to Assess Pollutant Exposure and Effects: A Case of Two Urban Rivers and a Wastewater Sedimentation Pond in Lake Victoria Basin
Omondi, Cornel A.; Omondi, Reuben; Onyango, Daniel W.; Obegi, Faith O.; Gichana, Zipporah
Aquatic ecosystem health assessment is critical for early detection of disturbances and water
habitat degradation. This study assessed the ecological status of two urban rivers as well a
wastewater sedimentation pond in Kisumu City, Kenya using physico-chemical water quality
parameters and the African catfish, Clarias gariepinus somatic indices. Site association of somatic
indices was derived from Principal Component Analysis (PCA) whereas the relationship between
water quality parameters was examined by Redundancy Ordination Analysis (RDA). PCA results
revealed an increase in Gill Somatic Index (GSI) in the wastewater sedimentation ponds while
Fulton’s Condition Factor (CF) increased in the midstream of Auji river and Kisat river mouth.
Similarly, RDA showed that dissolved oxygen, temperature, total phosphorus, alkalinity and total
nitrogen influenced the condition indices upstream of Kisat river and up-stream and midstream of
Auji river. However more impact on somatic indices were recorded in the wastewater
sedimentation pond. Although specific pollutants other than the physico-chemical parameters were
not identified, application of somatic indices in the African catfish demonstrated that the two rivers
as well as the wastewater sedimentation pond were contaminated by pollutants that can
compromise the ecological health of the aquatic systems. The results of this study emphasized the
negative impacts of anthropogenic activities on the environment.
Research Article on Use of Fish Somatic Indices to Assess
Pollutant Exposure and Effects
2024-01-16T00:00:00ZPhytochemicals from Pterocarpus angolensis DC and Their Cytotoxic Activities against Breast Cancer Cells
http://ir-library.kabianga.ac.ke/handle/123456789/791
Phytochemicals from Pterocarpus angolensis DC and Their Cytotoxic Activities against Breast Cancer Cells
Teclegeorgish, Zecarias W.; Mokgalaka, Ntebogeng S.; Kemboi, Douglas; Krause, Rui W. M.; Siwe-Noundou, Xavier; Nyemba, Getrude R.; Davison, Candace; de la Mare, Jo-Anne; Tembu, Vuyelwa J.
Pterocarpus anglonesis DC is an indigenous medicinal plant belonging to the Pterocarpus
genus of the Fabaceae family. It is used to treat stomach problems, headaches, mouth ulcers, malaria,
blackwater fever, gonorrhea, ringworm, diarrhea, heavy menstruation, and breast milk stimulation.
Column chromatography of the stem bark extracts resulted in the isolation of eight compounds,
which included friedelan-3-one (1), 3α-hydroxyfriedel-2-one (2), 3-hydroxyfriedel-3-en-2-one (3),
lup-20(29)-en-3-ol (4), Stigmasta-5-22-dien-3-ol (5), 4-O-methylangolensis (6), (3β)-3-acetoxyolean-12-
en-28-oic acid (7), and tetradecyl (E)-ferulate (8). The structures were established based on NMR, IR,
and MS spectroscopic analyses. Triple-negative breast cancer (HCC70), hormone receptor-positive
breast cancer (MCF-7), and non-cancerous mammary epithelial cell lines (MCF-12A) were used to
test the compounds’ cytotoxicity. Overall, the compounds showed either no toxicity or very low
toxicity to all three cell lines tested, except for the moderate toxicity displayed by lupeol (4) towards
the non-cancerous MCF-12A cells, with an IC50 value of 36.60 µM. Compound (3β)-3-acetoxyolean12-en-28-oic acid (7) was more toxic towards hormone-responsive (MCF-7) breast cancer cells than
either triple-negative breast cancer (HCC70) or non-cancerous breast epithelial (MCF-12A) cells (IC50
values of 83.06 vs. 146.80 and 143.00 µM, respectively).
Article on Phytochemicals from Pterocarpus angolensis DC and Their
Cytotoxic Activities against Breast Cancer Cells
2024-01-19T00:00:00ZRepellent effects of the essential oils of Cymbopogon citratus and Tagetes minuta on the sandfly, Phlebotomus duboscqi
http://ir-library.kabianga.ac.ke/handle/123456789/790
Repellent effects of the essential oils of Cymbopogon citratus and Tagetes minuta on the sandfly, Phlebotomus duboscqi
Kimutai, Albert; Ngeiywa, Moses; Mulaa, Margaret; Njagi, Peter G. N.; Ingonga, Johnstone; Nyamwamu, Lydia B.; Ombati, Cyprian; Ngumbi, Philip
Background: The sandfly, Phlebotomus duboscqi is a vector of zoonotic cutaneous leishmaniasis (ZCL) that is an
important public health problem in Eastern Africa. Repellents have been used for protection of humans against vectors of ZCL and other vectors that transmit killer diseases including malaria, Rift Valley fever, dengue, and yellow fever.
The repellent effects of different doses of the essential oils from the lemon grass, Cymbopogon citratus and Mexican
marigold, Tagetes minuta were evaluated in a two-chamber bioassay against 3- to 7-day-old unfed females of P.
duboscqi in the laboratory. The results were compared with those that were obtained when test animals were treated
with an equivalent dose of diethyl-3-methylbenzamide, which is a repellent that is commonly used as a positive
control.
Results: Overall, percentage repellency increased with increasing doses of the essential oils while biting rates
decreased with increasing concentrations of the oils. Further, the oil of C. citratus was more potent than that of T.
minuta with regard to protection time and biting deterrence. The effective doses at 50% (ED50) and at 90% (ED90) for
the oil of C. citratus, were 0.04 and 0.79 mg/ml, respectively. Those of the oil of T. minuta were 0.10 and 12.58 mg/ml.
In addition, the percentage repellency of 1 mg/ml of the essential oils of C. citratus and T. minuta against sandflies
was 100% and 88.89%, respectively. A lower dose of 0.5 mg/ml of the oils, elicited 89.13% repellency for C. citratus and
52.22% for T. minuta.
Conclusion: The laboratory tests showed that the essential oils of the two plants were highly repellent to adult sand
flies, P. duboscqi. Thus, the two essential oils are candidate natural repellents that can be used against P. duboscqi due
to their high efficacy at very low doses, hence, the envisaged safety in their use over chemical repellents. It remains
to carry out clinical studies on human subjects with appropriate formulations of the oils prior to recommending their
adoption for use against the sandflies.
Article Research on Repellent effects of the essential oils
of Cymbopogon citratus and Tagetes minuta
on the sandfly, Phlebotomus duboscqi
2017-01-01T00:00:00Z